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Targeting miR-337 mitigates disuse-induced bone loss

Abstract Disuse-induced bone loss occurs in long-term bed-ridden patients and in astronauts during spaceflight. The underlying mechanisms are poorly understood. In a rodent model of disuse-induced bone loss (called hindlimb unloading (HU)), we observed that decreased numbers of leptin receptor (LepR...

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Principais autores: Jiao Li, Ding Ma, Chunxue Zhang, Xueling Zheng, Ruihan Hao, Bin Zuo, Fei Xiao, Yang Li, Yuhang Liu, Zhouyi Duan, Yao Xiong, Orion R. Fan, Wenmin Zhu, Liming Dai, Bingjun Zhang, Yi Eve Sun, Xiaoling Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2025-08-01
coleção:Cell Discovery
Acesso em linha:https://doi.org/10.1038/s41421-025-00822-z
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