Genetics of Hypercholesterolemia: Comparison Between Familial Hypercholesterolemia and Hypercholesterolemia Nonrelated to LDL Receptor

Severe hypercholesterolemia (HC) is defined as an elevation of total cholesterol (TC) due to the increase in LDL cholesterol (LDL-C) >95th percentile or 190 mg/dl. The high values of LDL-C, especially when it is maintained over time, is considered a risk factor for the development of atherosclero...

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Autori principali:	Estíbaliz Jarauta, Ana Ma Bea-Sanz, Victoria Marco-Benedi, Itziar Lamiquiz-Moneo
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2020-12-01
Serie:	Frontiers in Genetics
Soggetti:	primary hypercholesterolemia familial hypercholesterolemia polygenic hypercholesterolemia cardiovascular disease LDL-cholesterol atherosclerosis
Accesso online:	https://www.frontiersin.org/articles/10.3389/fgene.2020.554931/full
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