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The Landscape of IFN/ISG Signaling in HIV-1-Infected Macrophages and Its Possible Role in the HIV-1 Latency

A key characteristic of Human immunodeficiency virus type 1 (HIV-1) infection is the generation of latent viral reservoirs, which have been associated with chronic immune activation and sustained inflammation. Macrophages play a protagonist role in this context since they are persistently infected w...

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Autori principali: Masyelly Rojas, Patricia Luz-Crawford, Ricardo Soto-Rifo, Sebastián Reyes-Cerpa, Daniela Toro-Ascuy
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2021-09-01
Serie:Cells
Soggetti:
HIV
latent HIV-1 reservoir
macrophages
IFN/ISG response
epitranscriptomic regulation
Accesso online:https://www.mdpi.com/2073-4409/10/9/2378
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