The spliceosome as a new therapeutic vulnerability in aggressive prostate cancer
Alternative splicing (AS) analysis across the entire spectrum of human prostate cancer evolution reveals the unexpected findings that intron retention is a hallmark of stemness and tumor aggressiveness, and androgen receptor controls a splicing program distinct from its transcriptional regulation. I...
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| Principais autores: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis Group
2020-09-01
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| Serier: | Molecular & Cellular Oncology |
| Fag: | |
| Online adgang: | http://dx.doi.org/10.1080/23723556.2020.1778420 |
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