FIGL1 and its novel partner FLIP form a conserved complex that regulates homologous recombination.

Homologous recombination is central to repair DNA double-strand breaks, either accidently arising in mitotic cells or in a programed manner at meiosis. Crossovers resulting from the repair of meiotic breaks are essential for proper chromosome segregation and increase genetic diversity of the progeny...

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Detalhes bibliográficos

Principais autores:	Joiselle Blanche Fernandes, Marine Duhamel, Mathilde Seguéla-Arnaud, Nicole Froger, Chloé Girard, Sandrine Choinard, Victor Solier, Nancy De Winne, Geert De Jaeger, Kris Gevaert, Philippe Andrey, Mathilde Grelon, Raphael Guerois, Rajeev Kumar, Raphaël Mercier
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2018-04-01
Colecção:	PLoS Genetics
Acesso em linha:	http://europepmc.org/articles/PMC5897033?pdf=render
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