Ferroptosis in orthopedic implant integration after oncologic surgery

Primary bone cancer treatment often requires large bone resections followed by reconstruction using orthopedic implants, which are usually made of titanium (Ti). In oncologic patients, the bone-implant interface (BII) microenvironment is compromised by adjuvant therapies, such as chemotherapy and ra...

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Autors principals:	Pierre-Olivier Karbonowski, Gwan Yong Lim, Karolina Lach, Michał Skrzycki, Magdalena Mielczarek-Puta
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-03-01
Col·lecció:	Frontiers in Oncology
Matèries:	bone remodeling ferroptosis orthopedic oncology reactive oxygen species surface coatings titanium implants
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fonc.2026.1811290/full
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