Characteristics and impact of infiltration of B-cells from systemic sclerosis patients in a 3D healthy skin model

IntroductionIn systemic sclerosis (SSc), B-cells are activated and present in the skin and lung of patients where they can interact with fibroblasts. The precise impact and mechanisms of the interaction of B-cells and fibroblasts at the tissular level are poorly studied.ObjectiveWe investigated the...

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Principais autores:	Mathilde Le Maître, Thomas Guerrier, Aurore Collet, Mehdi Derhourhi, Jean-Pascal Meneboo, Bénédicte Toussaint, Amélie Bonnefond, Céline Villenet, Shéhérazade Sebda, Antonino Bongiovanni, Meryem Tardivel, Myriam Simon, Manel Jendoubi, Blanche Daunou, Alexis Largy, Martin Figeac, Sylvain Dubucquoi, David Launay
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2024-08-01
coleção:	Frontiers in Immunology
Assuntos:	B-cell systemic sclerosis skin 3D coculture fibrosis fibroblast
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1373464/full
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