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Delineating phenotypic heterogeneity in human regulatory T cells across developmental stages and therapeutic sources

BackgroundFOXP3+ regulatory T cells (Tregs) play a pivotal role in maintaining immune homeostasis and self-tolerance. Despite advances in Treg-based immunosuppressive therapies, precise identification of human Tregs facilitating their isolation with high purity remains challenging because canonical...

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Principais autores: Samikshya Santosh Nirmala, Yueyuan Hu, Friederike Dorothea Floegel, Hugo Cruz, Johanna Morgenstern, Alexander Platz, Marcel Vollroth, Anke Fuchs
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2026-01-01
Serija:Frontiers in Immunology
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Online dostop:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1697723/full
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