Targeting triple‐negative breast cancer with an aptamer‐functionalized nanoformulation: a synergistic treatment that combines photodynamic and bioreductive therapies

Abstract Background Areas of hypoxia are often found in triple-negative breast cancer (TNBC), it is thus more difficult to treat than other types of breast cancer, and may require combination therapies. A new strategy that combined bioreductive therapy with photodynamic therapy (PDT) was developed h...

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Auteurs principaux:	Yi-Te Chou, Chih-Yu Lin, Jyun-Wei Wen, Ling-Chun Hung, Ying-Feng Chang, Chia-Min Yang, Li-chen Wu, Ja-an Annie Ho
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2021-03-01
Collection:	Journal of Nanobiotechnology
Sujets:	Triple‐negative breast cancer Photodynamic therapy Tumor hypoxia Bioreductive prodrug Hollow mesoporous silica nanoparticle DNA aptamer
Accès en ligne:	https://doi.org/10.1186/s12951-021-00786-8
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