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Identifying Promising Novel Compounds Against Free-Living Amoebae: A Systematic Review of In Vitro and In Vivo Studies

The increasing global incidence of infections caused by free-living amoebae (FLA) and the lack of effective, safe, and approved treatments highlight the urgent need for novel amoebicidal compounds with pharmacological potential. Despite a growing body of literature on the anti-FLA properties of vari...

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Main Authors: Beni Jequicene Mussengue Chaúque, Thaisla Cristiane Borella da Silva, Luiza Bernardes Chagas, Letícia F. G. Kinape, Paula Eliete Rodrigues Bitencourt, Custódio José Gaspar, Alexandre Coelho Borges Cheinquer, Marilise Brittes Rott, Régis Adriel Zanette, José Roberto Goldim
Format: Artigo
Language:Inglês
Published: MDPI AG 2025-10-01
Series:Parasitologia
Subjects:
<i>Balamuthia mandrillaris</i>
<i>Naegleria fowleri</i>
<i>Acanthamoeba</i> spp.
drug development
in vitro
in vivo
Online Access:https://www.mdpi.com/2673-6772/5/4/56
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