Transneuronal delivery of hyper-interleukin-6 enables functional recovery after severe spinal cord injury in mice
The CNS has limited ability to regenerate following injury, Here, the authors show that a single injection of AAV-hyper-interleukin-6 in the sensory motor cortex results in corticospinal and raphe spinal tracts regeneration in the injured spinal cord as well as functional recovery in mice.
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2021-01-01
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| coleção: | Nature Communications |
| Acesso em linha: | https://doi.org/10.1038/s41467-020-20112-4 |
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