Vascular adhesion molecule 1+ fibro-adipogenic progenitors mark fatty infiltration in chronic limb-threatening ischemia

Background: Skeletal muscle health and function are critical determinants of clinical outcomes in peripheral arterial disease. Chronic limb-threatening ischemia (CLTI), the most severe clinical manifestation of peripheral arterial disease, is associated with a 1-year amputation rate of 25%. In patie...

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Detalhes bibliográficos

Principais autores:	Qunsheng Dai, MD, Changxin Wan, PhD, Yueyuan Xu, PhD, Kaileen Fei, MD, Lindsey A. Olivere, MD, Hana Shafique, BS, BA, Shaghayegh Sadeghmousavi, MD, Camryn Johnson, BS, Brianna Garrett, MS, Leo Akers, MS, Derek Peters, MD, PhD, James Otto, PhD, Christopher D. Kontos, MD, Zhiceng Ji, PhD, Yarui Diao, PhD, Kevin W. Southerland, MD
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-01-01
coleção:	JVS - Vascular Science
Assuntos:	Peripheral arterial disease Chronic limb-threatening ischemia Amputation Myosteatosis Fibro-adipogenic progenitors
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2666350325000161
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