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Nanoscale architecture and coordination of actin cores within the sealing zone of human osteoclasts

Osteoclasts are unique in their capacity to degrade bone tissue. To achieve this process, osteoclasts form a specific structure called the sealing zone, which creates a close contact with bone and confines the release of protons and hydrolases for bone degradation. The sealing zone is composed of ac...

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Principais autores: Marion Portes, Thomas Mangeat, Natacha Escallier, Ophélie Dufrancais, Brigitte Raynaud-Messina, Christophe Thibault, Isabelle Maridonneau-Parini, Christel Vérollet, Renaud Poincloux
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications Ltd 2022-06-01
Serier:eLife
Fag:
osteoclast
nanoscale
sealing zone
actin
super resolution microscopy
Online adgang:https://elifesciences.org/articles/75610
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