Usage Pattern of Carbamazepine and Associated Severe Cutaneous Adverse Reactions in Singapore Following Implementation of HLA-B*15:02 Genotyping as Standard-of-Care

In April 2013, the Ministry of Health and Health Sciences Authority of Singapore jointly issued recommendations for HLA-B*15:02 genotyping before starting carbamazepine (CBZ) in new patients of Asian ancestry as standard of care. The Ministry of Health also approved a 75% subsidy for HLA-B*15:02 gen...

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Principais autores:	Cynthia Sung, Liesbet Tan, Michael Limenta, Ganga Ganesan, Dorothy Toh, Cheng Leng Chan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2020-05-01
Colecção:	Frontiers in Pharmacology
Assuntos:	HLA-B*15:02 carbamazepine levetiracetam Steven–Johnson syndrome toxic epidermal necrolysis (Stevens–Johnson syndrome/toxic epidermal necrolysis) serious cutaneous skin reactions
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fphar.2020.00527/full
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