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Bruton’s Tyrosine Kinase, a Component of B Cell Signaling Pathways, Has Multiple Roles in the Pathogenesis of Lupus

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the loss of adaptive immune tolerance to nucleic acid-containing antigens. The resulting autoantibodies form immune complexes that promote inflammation and tissue damage. Defining the signals that drive pathogenic autoantib...

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Sábháilte in:
Sonraí bibleagrafaíochta
Príomhchruthaitheoir: Anne B. Satterthwaite
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Frontiers Media S.A. 2018-01-01
Sraith:Frontiers in Immunology
Ábhair:
Rochtain ar líne:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01986/full
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