Genomic characterization reveals distinct mutational landscapes and therapeutic implications between different molecular subtypes of triple-negative breast cancer

Abstract Triple-negative breast cancer (TNBC) has high heterogeneity, poor prognosis, and limited treatment success. Recently, an immunohistochemistry-based surrogate classification for the “Fudan University Shanghai Cancer Center (FUSCC) subtyping” has been developed and is considered more suitable...

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Principais autores:	Ruo Qi Li, Lei Yan, Ling Zhang, Hai Xia Ma, Hui Wen Wang, Peng Bu, Yan Feng Xi, Jing Lian
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Portfolio 2024-05-01
Serija:	Scientific Reports
Teme:	Triple-negative breast cancer Targeted next-generation sequencing Genomic characterization Therapeutic implications
Online dostop:	https://doi.org/10.1038/s41598-024-62991-3
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