Developing a process of lentivirus purification from recombinant fluids using peptide affinity ligands

Abstract Lentiviral vectors (LVVs) are emerging as an enabling tool in gene and cell therapies, yet the toolkit for purifying them at scale is still immature. A pivoting moment in LVV isolation technology was marked by the introduction of affinity ligands for LVVs pseudo‐typed with Vesicular Stomati...

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Hlavní autoři:	Eduardo Barbieri, Gina N. Mollica, Sobhana A. Sripada, Shrirarjun Shastry, Yuxuan Wu, Arianna Minzoni, Will Smith, Elena Wuestenhagen, Annika Aldinger, Heiner Graalfs, Michael S. Crapanzano, Oliver Rammo, Michael M. Schulte, Michael A. Daniele, Stefano Menegatti
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2025-11-01
Edice:	Bioengineering & Translational Medicine
Témata:	affinity chromatography lentivirus membrane chromatography peptide ligands product polishing
On-line přístup:	https://doi.org/10.1002/btm2.70017
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