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Oxidative Stress and Cellular Senescence Are Involved in the Aging Kidney

Chronic kidney disease (CKD) can be considered as a clinical model for premature aging. However, non-invasive biomarkers to detect early kidney damage and the onset of a senescent phenotype are lacking. Most of the preclinical senescence studies in aging have been done in very old mice. Furthermore,...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Laura Marquez-Exposito, Lucia Tejedor-Santamaria, Floris A. Valentijn, Antonio Tejera-Muñoz, Sandra Rayego-Mateos, Vanessa Marchant, Raul R. Rodrigues-Diez, Irene Rubio-Soto, Sebastiaan N. Knoppert, Alberto Ortiz, Adrian M. Ramos, Roel Goldschmeding, Marta Ruiz-Ortega
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2022-01-01
Schriftenreihe:Antioxidants
Schlagworte:
cellular senescence
NRF2
aging kidney
oxidation
inflammaging
fibrosis
Online-Zugang:https://www.mdpi.com/2076-3921/11/2/301
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