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DNA methylation associated with the serum alanine aminotransferase concentration: evidence from Chinese monozygotic twins

Abstract Background To identify nongenetic factors influences on DNA methylation (DNAm) variations associated with blood Alanine Aminotransferase (ALT) concentration, this study conducted an epigenome-wide association study (EWAS) on Chinese monozygotic twins. Methods A total of 61 pairs of Chinese...

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Principais autores: Jingxian Li, Jia Luo, Tong Wang, Xiaocao Tian, Chunsheng Xu, Weijing Wang, Dongfeng Zhang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-04-01
Serier:Clinical Epigenetics
Fag:
Alanine aminotransferase
Causality
DNA methylation
Monozygotic twins
Online adgang:https://doi.org/10.1186/s13148-025-01869-1
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