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Insights into Early-Pregnancy Mechanisms: Mast Cells and Chymase CMA1 Shape the Phenotype and Modulate the Functionality of Human Trophoblast Cells, Vascular Smooth-Muscle Cells and Endothelial Cells

Spiral-artery (SA) remodeling is a fundamental process during pregnancy that involves the action of cells of the initial vessel, such as vascular smooth-muscle cells (VSMCs) and endothelial cells, but also maternal immune cells and fetal extravillous trophoblast cells (EVTs). Mast cells (MCs), and s...

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Autori principali: Ningjuan Zhang, Anne Schumacher, Beate Fink, Mario Bauer, Ana Claudia Zenclussen, Nicole Meyer
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2022-03-01
Serie:Cells
Soggetti:
chymase CMA1
mast cells
spiral arteries
extravillous trophoblast cells
endothelial cells
vascular smooth-muscle cells
Accesso online:https://www.mdpi.com/2073-4409/11/7/1158
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