Evaluation of Hydroxycarboxylic Acid Receptor 1 (HCAR1) as a Building Block for Genetically Encoded Extracellular Lactate Biosensors

The status of lactate has evolved from being considered a waste product of cellular metabolism to a useful metabolic substrate and, more recently, to a signaling molecule. The fluctuations of lactate levels within biological tissues, in particular in the interstitial space, are crucial to assess wit...

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Hlavní autoři:	Joel Wellbourne-Wood, Marc Briquet, Maxime Alessandri, Francesca Binda, Maylis Touya, Jean-Yves Chatton
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2022-02-01
Edice:	Biosensors
Témata:	lactate genetically encoded fluorescent indicator GPR81 HCAR1 circularly permuted green fluorescent protein
On-line přístup:	https://www.mdpi.com/2079-6374/12/3/143
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