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Lipidopathy disrupts peripheral and central amyloid clearance in Alzheimer's disease: Where are our knowledge

Amyloid-beta (Aβ) production is a normal physiological process, essential for neuronal function. However, an imbalance in Aβ production and clearance is the central pathological feature of Alzheimer’s disease (AD), leading to the accumulation of Aβ plaques in the brain. Low-density lipoprotein recep...

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Bibliografiske detaljer
Principais autores: Shahram Darabi, Enam Alhagh Charkhat Gorgich, Fatemeh Moradi, Auob Rustamzadeh
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2025-06-01
Serier:IBRO Neuroscience Reports
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Online adgang:http://www.sciencedirect.com/science/article/pii/S2667242125000053
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