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The Histone H3 K4me3, K27me3, and K27ac Genome-Wide Distributions Are Differently Influenced by Sex in Brain Cortexes and Gastrocnemius of the Alzheimer’s Disease PSAPP Mouse Model

Background: Women represent the majority of Alzheimer’s disease patients and show typical symptoms. Genetic, hormonal, and behavioral mechanisms have been proposed to explain sex differences in dementia prevalence. However, whether sex differences exist in the epigenetic landscape of neuronal tissue...

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Principais autores: Francesca Casciaro, Giuseppe Persico, Martina Rusin, Stefano Amatori, Claire Montgomery, Jennifer R. Rutkowsky, Jon J. Ramsey, Gino Cortopassi, Mirco Fanelli, Marco Giorgio
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2021-11-01
Serija:Epigenomes
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Online dostop:https://www.mdpi.com/2075-4655/5/4/26
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