Angiopoietin receptor Tie2 is required for vein specification and maintenance via regulating COUP-TFII
Mechanisms underlying the vein development remain largely unknown. Tie2 signaling mediates endothelial cell (EC) survival and vascular maturation and its activating mutations are linked to venous malformations. Here we show that vein formation are disrupted in mouse skin and mesentery when Tie2 sign...
I tiakina i:
| Ngā kaituhi matua: | , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
eLife Sciences Publications Ltd
2016-12-01
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| Rangatū: | eLife |
| Ngā marau: | |
| Urunga tuihono: | https://elifesciences.org/articles/21032 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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