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OBJECTIVES/SPECIFIC AIMS: Accumulation of cholesterol-laden macrophages in arterial walls leads to atherosclerosis. LXRs induce expression of genes that are atheroprotective in macrophages including CCR7, a chemokine receptor that promotes their emigration from the plaque. CCR7 expression has been s...
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| Huvudupphov: | , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Cambridge University Press
2017-09-01
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| Serie: | Journal of Clinical and Translational Science |
| Länkar: | https://www.cambridge.org/core/product/identifier/S2059866117000346/type/journal_article |
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