Aberrant fucosylation of extracellular vesicles remodels the vascular microenvironment and promotes chemoresistance in myelodysplastic syndromes and acute myeloid leukemia

Primary resistance to hypomethylating agents (HMAs) remains a major obstacle in the treatment of elderly patients with myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). An altered integrity of the vascular wall is suspected to contribute to this resistance, yet the underlying molecu...

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Principais autores:	Jingjing Feng, Kexin Wang, Junjie Gou, Yi Wang, Bowen Hu, Wei Wei, Junqi Ge, Yanli Feng, Shuang Feng, Eric Solary, Feng Guan, Xiang Li
Formato:	Artigo
Idioma:	Inglês
Publicado:	Ferrata Storti Foundation 2026-03-01
Series:	Haematologica
Acceso en liña:	https://haematologica.org/article/view/13368
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