α-synuclein and tau: interactions, cross-seeding, and the redefinition of synucleinopathies as complex proteinopathies

Neurodegenerative diseases are characterized by protein aggregation and overlapping pathologies, challenging traditional classifications and highlighting shared underlying mechanisms. Parkinson’s disease and related synucleinopathies, including Lewy body dementia and multiple system atrophy, highlig...

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Principais autores:	Francisco J. Padilla-Godínez, Eunice Ruth Vázquez-García, María Isabel Trujillo-Villagrán, Luis O. Soto-Rojas, Marcela Palomero-Rivero, Omar Hernández-González, Francisco Pérez-Eugenio, Omar Collazo-Navarrete, Oscar Arias-Carrión, Magdalena Guerra-Crespo
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2025-03-01
Series:	Frontiers in Neuroscience
Assuntos:	α-synuclein tau synucleinopathy tauopathy proteinopathy Lewy bodies
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fnins.2025.1570553/full
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