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Blood and tissue correlates of steroid non-response in checkpoint inhibition-induced immune-related adverse events

Abstract Background High-dose steroids constitute the cornerstone of first-line treatment for immune-related adverse events (irAEs) associated with immune checkpoint inhibitors, but compromise antitumor immunity. A deeper understanding of irAEs and their response to steroids can improve management....

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Principais autores: Mick J. M. van Eijs, M. Marlot van der Wal, Hedi-Britt Klotškova, Noël M. M. Dautzenberg, Mark Schuiveling, Rik J. Verheijden, Fiona D. M. van Schaik, Bas Oldenburg, Stefan Nierkens, the UNICIT Consortium, Karijn P. M. Suijkerbuijk, Femke van Wijk
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2025-11-01
coleção:Communications Medicine
Acesso em linha:https://doi.org/10.1038/s43856-025-01164-3
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