Polymerized laminin-modified microcapsules improve pancreatic islet resilience towards cytokine induced inflammatory stress and lower chemoattractant cytokine secretion

Encapsulation of human pancreatic islets in semipermeable membranes offers a promising, less invasive alternative to whole pancreas transplantation for Type 1 Diabetes (T1D), potentially reducing the need for immunosuppressive drugs and improving graft survival. However, the inflammatory environment...

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Detalhes bibliográficos

Principais autores:	Isaura Beatriz Borges Silva, Theo Borghuis, Tian Qin, Mari Cleide Sogayar, Paul de Vos
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-06-01
Colecção:	Materials Today Bio
Assuntos:	Encapsulation Type 1 Diabetes Extracellular matrix Islet transplantation Laminin
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2590006425003722
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