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In Vitro and In Vivo Antitumor Activity of [Pt(O,O'-acac)(γ-acac)(DMS)] in Malignant Pleural Mesothelioma.

Malignant pleural mesothelioma (MPM) is an aggressive malignancy highly resistant to chemotherapy. There is an urgent need for effective therapy inasmuch as resistance, intrinsic and acquired, to conventional therapies is common. Among Pt(II) antitumor drugs, [Pt(O,O'-acac)(γ-acac)(DMS)] (Ptac2S) ha...

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Detalles Bibliográficos
Principais autores: Antonella Muscella, Carla Vetrugno, Luca Giulio Cossa, Giovanna Antonaci, Francesco De Nuccio, Sandra Angelica De Pascali, Francesco Paolo Fanizzi, Santo Marsigliante
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Acceso en liña:https://doi.org/10.1371/journal.pone.0165154
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