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The loss of neoantigens is an important reason for immune escape in multiple myeloma patients with high intratumor heterogeneity

Abstract Objectives Intratumor heterogeneity (ITH) is an important factor for clinical outcomes in patients with multiple myeloma (MM). High ITH has been proven to be a key reason for tumor immune escape and treatment resistance. Neoantigens are thought to be associated with ITH, but the specific co...

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Detalles Bibliográficos
Principais autores: Yue Wang, Jiadai Xu, Tianwei Lan, Chi Zhou, Peng Liu
Formato: Artigo
Idioma:Inglês
Publicado: Wiley 2023-12-01
Series:Cancer Medicine
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Acceso en liña:https://doi.org/10.1002/cam4.6721
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