Nucleolus and centromere Tyramide Signal Amplification-Seq reveals variable localization of heterochromatin in different cell types

Abstract Genome differential positioning within interphase nuclei remains poorly explored. We extended and validated Tyramide Signal Amplification (TSA)-seq to map genomic regions near nucleoli and pericentric heterochromatin in four human cell lines. Our study confirmed that smaller chromosomes loc...

Полное описание

Библиографические подробности

Главные авторы:	Pradeep Kumar, Omid Gholamalamdari, Yang Zhang, Liguo Zhang, Anastassiia Vertii, Tom van Schaik, Daan Peric-Hupkes, Takayo Sasaki, David M. Gilbert, Bas van Steensel, Jian Ma, Paul D. Kaufman, Andrew S. Belmont
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Nature Portfolio 2024-09-01
Серии:	Communications Biology
Online-ссылка:	https://doi.org/10.1038/s42003-024-06838-7
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!