Chromatin regulation in schistosomes and histone modifying enzymes as drug targets

Only one drug is currently available for the treatment and control of schistosomiasis and the increasing risk of selecting strains of schistosome that are resistant to praziquantel means that the development of new drugs is urgent. With this objective we have chosen to target the enzymes modifying h...

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Bibliografiske detaljer

Principais autores:	Raymond John Pierce, Florence Dubois-Abdesselem, Stéphanie Caby, Jacques Trolet, Julien Lancelot, Frédérik Oger, Nicolas Bertheaume, Emmanuel Roger
Format:	Artigo
Sprog:	Inglês
Udgivet:	Fundação Oswaldo Cruz (FIOCRUZ) 2011-11-01
Serier:	Memorias do Instituto Oswaldo Cruz
Fag:	Schistosoma mansoni histone modifying enzyme histone deacetylase inhibitor drug target
Online adgang:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000700003&lng=en&tlng=en
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