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Identification of biomarkers of brown adipose tissue aging highlights the role of dysfunctional energy and nucleotide metabolism pathways

Abstract Brown adipose tissue function declines during aging and may contribute to the onset of metabolic disorders such as diabetes and obesity. Only limited understanding of the mechanisms leading to the metabolic impairment of brown adipocytes during aging exists. To this end, interscapular brown...

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Autori principali: Carola Mancini, Sabrina Gohlke, Francisco Garcia-Carrizo, Vyacheslav Zagoriy, Heike Stephanowitz, Tim J. Schulz
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2021-10-01
Serie:Scientific Reports
Accesso online:https://doi.org/10.1038/s41598-021-99362-1
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