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Reduced Toxicity of Shiga Toxin (Stx) Type 2c in Mice Compared to Stx2d Is Associated with Instability of Stx2c Holotoxin

Shiga toxin (Stx) is an AB5 ribotoxin made by Stx-producing Escherichia coli (STEC). These organisms cause diarrhea, hemorrhagic colitis and the hemolytic uremic syndrome. STEC make two types of Stxs, Stx1 and/or Stx2. Stx2 has one prototype (a) and six subtypes (b–g), but only STEC that make Stx2a,...

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Bibliografiske detaljer
Principais autores: Joshua C. Bunger, Angela R. Melton-Celsa, Ernest L. Maynard, Alison D. O'Brien
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2015-06-01
Serier:Toxins
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Online adgang:http://www.mdpi.com/2072-6651/7/6/2306
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