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Hepatitis C virus replication and Golgi function in brefeldin a-resistant hepatoma-derived cells.

Recent reports indicate that the replication of hepatitis C virus (HCV) depends on the GBF1-Arf1-COP-I pathway. We generated Huh-7-derived cell lines resistant to brefeldin A (BFA), which is an inhibitor of this pathway. The resistant cell lines could be sorted into two phenotypes regarding BFA-indu...

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Bibliografiske detaljer
Principais autores: Rayan Farhat, Lucie Goueslain, Czeslaw Wychowski, Sandrine Belouzard, Lucie Fénéant, Catherine L Jackson, Jean Dubuisson, Yves Rouillé
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2013-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC3776844?pdf=render
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