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An epigenetic switch involving overlapping fur and DNA methylation optimizes expression of a type VI secretion gene cluster.

Type VI secretion systems (T6SS) are macromolecular machines of the cell envelope of Gram-negative bacteria responsible for bacterial killing and/or virulence towards different host cells. Here, we characterized the regulatory mechanism underlying expression of the enteroagregative Escherichia coli...

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Principais autores: Yannick R Brunet, Christophe S Bernard, Marthe Gavioli, Roland Lloubès, Eric Cascales
格式: Artigo
语言:Inglês
出版: Public Library of Science (PLoS) 2011-07-01
丛编:PLoS Genetics
在线阅读:http://europepmc.org/articles/PMC3145626?pdf=render
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