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Bioactive Extracellular Matrix Scaffold Promotes Adaptive Cardiac Remodeling and Repair

Structural cardiac remodeling after ischemic injury can induce a transition to heart failure from progressive loss of cardiac function. Cellular regenerative therapies are promising but face significant translational hurdles. Tissue extracellular matrix (ECM) holds the necessary environmental cues t...

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Autori principali: Holly E.M. Mewhort, MD, PhD, Daniyil A. Svystonyuk, BSc, Jeannine D. Turnbull, BSc, Guoqi Teng, PhD, Darrell D. Belke, PhD, David G. Guzzardi, BSc, Daniel S. Park, BSc, Sean Kang, BSc, Morley D. Hollenberg, MD, PhD, Paul W.M. Fedak, MD, PhD
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2017-08-01
Serie:JACC: Basic to Translational Science
Soggetti:
extracellular matrix
regeneration
vasculogenesis
Accesso online:http://www.sciencedirect.com/science/article/pii/S2452302X17301389
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