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First Identification of <i>BoLA-DRB3</i> Alleles Associated with Differential Susceptibility to Bovine Leukemia Virus Infection and Proviral Load in Chinese Holstein Cattle

Bovine leukemia virus (BLV), the most prevalent neoplastic disease of cattle worldwide, is the causative agent of enzootic bovine leukosis. Polymorphisms in the bovine leukocyte antigen (<i>BoLA</i>)<i>-DRB3</i> gene can influence host immune responses to pathogens, including BLV. However, the assoc...

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Main Authors: Jingyuan Wang, Ryosuke Matsuura, Sonoko Watanuki, Aronggaowa Bao, Noriko Fukushi, Yasunobu Matsumoto, Lin Dong, Guangjun Guo, Chunyang Yao, Changjiang Wang, Feng Wei, Jishan Liu, Xuebo Wang, Fengrong Tian, Jinliang Wang, Yoko Aida
Format: Artigo
Language:Inglês
Published: MDPI AG 2025-12-01
Series:Pathogens
Subjects:
<i>BoLA-DRB3</i>
bovine leukemia virus
proviral load
BLV infection
susceptibility
resistance
Online Access:https://www.mdpi.com/2076-0817/15/1/34
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