Enhancing antibiotic therapy through comprehensive pharmacokinetic/pharmacodynamic principles

Antibiotic therapy relies on understanding both pharmacokinetics (PK) and pharmacodynamics (PD), which respectively address drug absorption, distribution, and elimination, and the relationship between drug concentration and antimicrobial efficacy. This review synthesizes decades of research, drawing...

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Auteurs principaux:	Mohammad Sina Alikhani, Mohsen Nazari, Shima Hatamkhani
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2025-02-01
Collection:	Frontiers in Cellular and Infection Microbiology
Sujets:	pharmacokinetic pharmacodynamic antibiotics antimicrobial efficacy post-antibiotic effect
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fcimb.2025.1521091/full
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