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Blood–brain barrier disruption and ventricular enlargement are the earliest neuropathological changes in rats with repeated sub-concussive impacts over 2 weeks

Abstract Repeated sub-concussive impact (e.g. soccer ball heading), a significantly lighter form of mild traumatic brain injury, is increasingly suggested to cumulatively alter brain structure and compromise neurobehavioural function in the long-term. However, the underlying mechanisms whereby repea...

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Auteurs principaux: Bailey Hiles-Murison, Andrew P. Lavender, Mark J. Hackett, Joshua J. Armstrong, Michael Nesbit, Samuel Rawlings, Terrence McGonigle, Andrew Warnock, Virginie Lam, John C. L. Mamo, Melinda Fitzgerald, Ryu Takechi
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2021-04-01
Collection:Scientific Reports
Accès en ligne:https://doi.org/10.1038/s41598-021-88854-9
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