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Improved analysis of (e)CLIP data with RCRUNCH yields a compendium of RNA-binding protein binding sites and motifs

Abstract We present RCRUNCH, an end-to-end solution to CLIP data analysis for identification of binding sites and sequence specificity of RNA-binding proteins. RCRUNCH can analyze not only reads that map uniquely to the genome but also those that map to multiple genome locations or across splice bou...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Maria Katsantoni, Erik van Nimwegen, Mihaela Zavolan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2023-04-01
Cyfres:Genome Biology
Pynciau:
Mynediad Ar-lein:https://doi.org/10.1186/s13059-023-02913-0
Tagiau: Ychwanegu Tag
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