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Distinct T cell responsiveness to different COVID-19 vaccines and cross-reactivity to SARS-CoV-2 variants with age and CMV status

IntroductionAccumulating evidence indicates the importance of T cell immunity in vaccination-induced protection against severe COVID-19 disease, especially against SARS-CoV-2 Variants-of-Concern (VOCs) that more readily escape from recognition by neutralizing antibodies. However, there is limited kn...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Jolanda Brummelman, Sara Suárez-Hernández, Lia de Rond, Marjan Bogaard-van Maurik, Petra Molenaar, Emma van Wijlen, Debbie Oomen, Lisa Beckers, Nynke Y. Rots, Josine van Beek, Mioara A. Nicolaie, Cécile A. C. M. van Els, Mardi C. Boer, Patricia Kaaijk, Anne-Marie Buisman, Jelle de Wit
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2024-05-01
Schriftenreihe:Frontiers in Immunology
Schlagworte:
COVID-19
vaccine
mRNA
T cell response
CMV
age
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1392477/full
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