Incidence of non-colorectal/endometrial malignancies in individuals with Lynch syndrome: a retrospective cohort studyResearch in context

Summary: Background: Lynch syndrome (LS) is strongly associated with colorectal (CRC) and endometrial (EC) cancers, for which Universal Tumor Screening (UTS) via mismatch repair proteins (MMRs) immunohistochemistry is currently recommended. However, emerging evidence suggests an association between...

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Hlavní autoři:	Silvia Negro, Francesco Celotto, Francesca Schiavi, Marco Scarpa, Isabella Mammi, Silvia Rossi, Lorenzo Dell’Atti, Maria Caterina De Grandis, Gino Crivellari, Matteo Fassan, Marco Agostini, Gaya Spolverato, Filippo Cappello, Edoardo D'Angelo, Michele Milella, Maria Bencivenga, Pierluigi Pilati, Sara Lonardi, Rossana Intini, Valentina Guarneri, Maria Vittoria Dieci, Alberto Morabito, Daniela Barana, Alessandra D'Urso, Massimo Iafrate, Francesca Bergamo, Emanuele D.L. Urso
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2025-12-01
Edice:	EClinicalMedicine
Témata:	Lynch syndrome Universal tumor screening Non-colorectal/endometrial tumors Extracolonic malignancies Mismatch repair genes
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2589537025005528
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