Transition metals and oxidation reactions trigger stargate opening during the initial stages of the replicative cycle of the giant Tupanvirus

ABSTRACT Tupanviruses, members of the family Mimiviridae, infect phagocytic cells. Particle uncoating begins inside the phagosome, with capsid opening via the stargate. The mechanism through which this opening takes place is unknown. Once phagocytized, metal ion flux control and ROS are induced to i...

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Bibliografische Detailangaben

Hauptverfasser:	Juliana R. Cortines, Charles M. Bridges, Sundharraman Subramanian, Jason R. Schrad, Glauber R. S. Araújo, Gabriel Henrique Pereira Nunes, Juliana dos Santos Oliveira, Victor Alejandro Essus, Jônatas S. Abrahão, Simon White, Kristin N. Parent, Carolyn Teschke
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology 2024-10-01
Schriftenreihe:	mBio
Schlagworte:	Tupanvirus iron copper ROS nutritional immunity
Online-Zugang:	https://journals.asm.org/doi/10.1128/mbio.02192-24
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