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Adiponectin Inhibits Oxidative Stress and Tight Junction Protein Loss: Evidence from a Hepatic Encephalopathy Mouse Model and Brain Endothelial Cells

<b>Background/Objectives</b>: Hepatic encephalopathy (HE) is characterized by hyperammonemia, neuroinflammation, oxidative stress, and blood–brain barrier (BBB) dysfunction, with brain endothelial cells being highly vulnerable to ammonia-induced damage. Adiponectin is a cytoprotective adipokine that...

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Principais autores: Dong Jun Song, Seol Won Jeong, Seoyeon Ahn, Danbi Jo, Che-Hun Jung, Jiwoun Park, Sangjun Lee, Juhyun Song
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2026-03-01
Series:Pharmaceuticals
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Acceso en liña:https://www.mdpi.com/1424-8247/19/3/419
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