Crystal Structure of the Chloroplastic Glutamine Phosphoribosylpyrophosphate Amidotransferase GPRAT2 From Arabidopsis thaliana

Chloroplastic glutamine phosphoribosylpyrophosphate amidotransferase (GPRATase) catalyzes the first committed step of de novo purine biosynthesis in Arabidopsis thaliana, and DAS734 is a direct and specific inhibitor of AtGPRAT, with phytotoxic effects similar to the leaf beaching phenotypes of know...

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Autores principales:	Xueli Cao, Bowen Du, Fengjiao Han, Yu Zhou, Junhui Ren, Wenhe Wang, Zeliang Chen, Yi Zhang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2020-02-01
Colección:	Frontiers in Plant Science
Materias:	chloroplastic glutamine phosphoribosylpyrophosphate amidotransferase herbicide X-ray crystallography competitive inhibition Arabidopsis thaliana DAS734
Acceso en línea:	https://www.frontiersin.org/article/10.3389/fpls.2020.00157/full
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