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Integrative Network Pharmacology and Molecular Docking Analysis Uncovers Multi-Target Mechanisms of Alpha-Mangostin Against Acute Kidney Injury

Alpha-mangostin (AM), a xanthone from <i>Garcinia mangostana</i>, has shown promising nephroprotective properties, but its mechanisms in acute kidney injury (AKI) remain incompletely defined. In this study, we applied an integrative network pharmacology pipeline combined with molecular docking to cl...

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Principais autores: Moragot Chatatikun, Aman Tedasen, Chutima Jansakun, Passakorn Poolbua, Jason C. Huang, Jongkonnee Thanasai, Wiyada Kwanhian Klangbud, Atthaphong Phongphithakchai
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2026-04-01
Serier:Foods
Fag:
alpha-mangostin
acute kidney injury
<i>PTGS2</i>
network pharmacology
molecular docking
Online adgang:https://www.mdpi.com/2304-8158/15/7/1270
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