Durable clinical response to immunotherapy in EGFR-mutated lung adenocarcinoma with squamous cell carcinoma transformation and high expression of PD-L1 after resistance development: A case report

Histological transformation is one of the mechanisms of resistance to targeted therapy, chemotherapy and immunotherapy in non-small cell lung cancer (NSCLC). The histological transformation from adenocarcinoma (ADC) to squamous cell carcinoma (SCC) after tyrosine kinase inhibitor (TKI) treatment is...

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Bibliografische Detailangaben

Hauptverfasser:	Zhongsheng Peng, Yanjun Xu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2022-12-01
Schriftenreihe:	Current Problems in Cancer: Case Reports
Schlagworte:	Lung adenocarcinoma Histological transformation Squamous cell carcinoma EGFR Immune checkpoint inhibitor
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2666621922000631
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