Heparin modification of a biomimetic bone matrix modulates osteogenic and angiogenic cell response in vitro

In this study, the effect of heparin-modified collagen type I/hydroxyapatite (HA) nanocomposites on key processes of bone regeneration – osteogenesis and angiogenesis – was characterised in vitro. Two approaches were applied for heparin modification: it was either integrated during material synthesi...

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Detalhes bibliográficos

Principais autores:	M Quade, S Knaack, D Weber, U König, B Paul, P Simon, A Rösen-Wolff, R Schwartz-Albiez, M Gelinsky, A Lode
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Forum Multimedia Publishing LLC 2017-02-01
coleção:	European Cells & Materials
Assuntos:	collagen heparin hydroxyapatite endothelial cells mesenchymal stem cells osteogenic differentiation angiogenesis co-culture
Acesso em linha:	http://www.ecmjournal.org/papers/vol033/pdf/v033a08.pdf
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